Criminal Victimisation in Taiwan: an opportunity perspective

Environmental criminology concerns the role of opportunities (both people and objects) existing in the environment that make crimes more likely to occur. Research consistently shows that opportunity perspectives (particularly with regard to individuals’ lifestyles and routines) help in explaining the prevalence and concentration of crimes. However, there is a paucity of studies investigating crime patterns from an opportunity perspective both outside western countries and in relation to cybercrimes. Hence, it is not clear whether non-Western and online contexts exhibit similar patterns of crime as would be predicted by an opportunity perspective. This thesis is concerned with criminal victimisation in Taiwan – a less researched setting in the field of environmental criminology. It covers both offline victimisation (with a focus on burglary) and online victimisation from the aforementioned opportunity perspective. The goal of this thesis is to identify individual- and area-level characteristics that affect the patterns of victimisation in Taiwan. To achieve this, the thesis draws on a range of secondary datasets, including police recorded crime statistics, the Taiwan Area Victimisation Survey, and the Digital Opportunity Survey for Individuals and Households. With the application of quantitative modelling, the thesis suggests that the generalisability the lifestyle-routine activity approach in explaining crime patterns in Taiwan should be taken with caution. The findings provide partial support for its applicability in relation to burglary and cybercrime in Taiwan. Furthermore, the findings reported here in relation to patterns of repeat and near repeat victimisation depart from those observed in the western literature. The thesis concludes by discussing the implications of the findings for academic research and practice in crime prevention

Repeat and Near Repeat Burglary Victimization in Taiwan

Extensive evidence shows that repeat victimization is common and widespread, but studies on the prevalence of repeat victimization in Asia are limited. This study examines the extent and patterns of repeat and near-repeat burglary victimization in Taiwan using both 2015 Taiwan Area Victimization Survey data and police recorded burglary data. Results indicated that: (1) burglaries against the same household in Taiwan are highly concentrated (with the top 10% most burgled households making up around 30% of reported victimizations), more so than is often found in many Western countries; (2) the risk of (repeat) burglary is not consistently spread over space and time, particularly within the 100-m range of an initial burglary incident; and (3) the levels of near repeat burglaries identified in this study are notably lower than was observed in prior studies both in China and in many western countries. The findings highlight the value of developing prevention strategies specifically targeting repeat burglary victimization

DNMT3A (DNA (cytosine-5-)-methyltransferase 3 alpha)

Review on DNMT3A (DNA (cytosine-5-)-methyltransferase 3 alpha), with data on DNA, on the protein encoded, and where the gene is implicated

Undiagnosed diabetes mellitus among residents in Taiwanese long-term care facilities: A comparison of fasting glucose, postprandial plasma glucose, and hemoglobin A1c

AbstractBackgroundThe prevalence of diabetes mellitus (DM) is escalating with an aging population, and the chances of diabetic older patients admitted to long-term care facilities (LTCFs) are increased because of DM-related complications. However, undiagnosed DM among LTCF residents is a recognized hidden problem in this setting and may result in adverse outcomes.MethodsIn May 2011, 10 private LTCFs in northern Taipei participated in this study. Trained research nurses reviewed the medical records and performed physical examinations and blood sampling for all participants. Diabetes mellitus was diagnosed, based on the levels of fasting glucose, 2-hour postprandial plasma glucose, and hemoglobin A1c (HbA1c). Patients were categorized as having DM if they met the diagnostic cut-offs of the aforementioned criteria.ResultsOne hundred and ninety-nine residents (mean age, 79.6 ± 10.5 years; 52.3% males) participated in this study. They were all moderately/severely disabled (Karnofsky Performance Scale mean score was 50 ± 13). Forty-six (23.1%) residents were diabetic, based on their medical records, or were current users of antidiabetic agents. The prevalence was 29.6% after testing with a mean HbA1c level of 6.9% ± 0.9%. The overall undiagnosed DM rate was 4%, 3.5%, and 4.5%, based on fasting glucose, 2-hour postprandial plasma glucose, and HbA1c criteria, respectively. Diabetic patients had significantly higher serum levels of prealbumin, compared to nondiabetic patients (220.8 ± 45.9 vs. 201.1 ± 62.2 mg/L; p = 0.03), but there were no differences in the levels of hemoglobin, serum albumin, or total cholesterol. Diabetic patients had a significantly higher serum triglyceride level, compared to the nondiabetic patients (1.6 ± 0.7 vs. 1.1 ± 0.5 mmol/L; p < 0.01) and a lower high-density lipoprotein level (1.0 ± 0.3 vs. 1.2 ± 0.3 mmol/L; p < 0.01). Among 43 pharmacologically treated diabetic patients, 65.1% (28/43) of patients were using oral antidiabetic agents and 41.9% (18/43) of patients had been prescribed insulin, whereas 32.6% of the patients were managed by combination therapy.ConclusionThe prevalence of DM among LTCF residents in Taipei was 29.6%, and the undiagnosed rate was no more than 5%, based on fasting glucose, 2-hour postprandial plasma glucose, or HbA1c. Further study is needed for the optimal treatment strategy of DM in LTCFs

Predicting the Severity and Prognosis of Trismus after Intensity-Modulated Radiation Therapy for Oral Cancer Patients by Magnetic Resonance Imaging

To develop magnetic resonance imaging (MRI) indicators to predict trismus outcome for post-operative oral cavity cancer patients who received adjuvant intensity-modulated radiation therapy (IMRT), 22 patients with oral cancer treated with IMRT were studied over a two-year period. Signal abnormality scores (SA scores) were computed from Likert-type ratings of the abnormalities of nine masticator structures and compared with the Mann-Whitney U-test and Kruskal–Wallis one-way ANOVA test between groups. Seventeen patients (77.3%) experienced different degrees of trismus during the two-year follow-up period. The SA score correlated with the trismus grade (r = 0.52, p<0.005). Patients having progressive trismus had higher mean doses of radiation to multiple structures, including the masticator and lateral pterygoid muscles, and the parotid gland (p<0.05). In addition, this group also had higher SA-masticator muscle dose product at 6 months and SA scores at 12 months (p<0.05). At the optimum cut-off points of 0.38 for the propensity score, the sensitivity was 100% and the specificity was 93% for predicting the prognosis of the trismus patients. The SA score, as determined using MRI, can reflect the radiation injury and correlate to trismus severity. Together with the radiation dose, it could serve as a useful biomarker to predict the outcome and guide the management of trismus following radiation therapy

Small Odd Prime Field Multivariate PKCs

We show that Multivariate Public Key Cryptosystems (MPKCs) over fields of small odd prime characteristic, say 31, can be highly efficient. Indeed, at the same design security of $2^{80}$ under the best known attacks, odd-char MPKC is generally faster than prior MPKCs over \GF{2^k}, which are in turn faster than ``traditional\u27\u27 alternatives. This seemingly counter-intuitive feat is accomplished by exploiting the comparative over-abundance of small integer arithmetic resources in commodity hardware, here embodied by SSE2 or more advanced special multimedia instructions on modern x86-compatible CPUs. We explain our implementation techniques and design choices in implementing our chosen MPKC instances modulo small a odd prime. The same techniques are also applicable in modern FPGAs which often contains a large number of multipliers

A cytoplasmic RNA virus generates functional viral small RNAs and regulates viral IRES activity in mammalian cells

The roles of virus-derived small RNAs (vsRNAs) have been studied in plants and insects. However, the generation and function of small RNAs from cytoplasmic RNA viruses in mammalian cells remain unexplored. This study describes four vsRNAs that were detected in enterovirus 71-infected cells using next-generation sequencing and northern blots. Viral infection produced substantial levels (\u3e105 copy numbers per cell) of vsRNA1, one of the four vsRNAs. We also demonstrated that Dicer is involved in vsRNA1 generation in infected cells. vsRNA1 overexpression inhibited viral translation and internal ribosomal entry site (IRES) activity in infected cells. Conversely, blocking vsRNA1 enhanced viral yield and viral protein synthesis. We also present evidence that vsRNA1 targets stem-loop II of the viral 5′ untranslated region and inhibits the activity of the IRES through this sequence-specific targeting. Our study demonstrates the ability of a cytoplasmic RNA virus to generate functional vsRNA in mammalian cells. In addition, we also demonstrate a potential novel mechanism for a positive-stranded RNA virus to regulate viral translation: generating a vsRNA that targets the IRES